Antineutrophil cytoplasmic antibody in uveitis and scleritis

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antineutrophil cytoplasmic autoantibodies in uveitis

antineutrophil cytoplasmic autoantibodies were detected in patients with some autoimmune and vascular disease such as wegner’s granulomatosis polyarthritis nodosa and systemic lupus erythematosus. indirect immunofluorescence technique was employed to detect these autoantibodies. by this method, two general patterns of antineutrophil cytoplasmic autoantibodies were seen: a cytoplasmic (c-anca) a...

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The antineutrophil antibody in uveitis.

Ninety eight patients with uveitis of various types were tested for the presence of the antineutrophil antibody or ANCA by an indirect immunofluorescence method. This antibody is found in patients with diseases associated with small vessel vasculitis, including Wegener's granulomatosis and microscopic polyarteritis. Eleven true positive cases were found. A positive test was not associated with ...

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A patient with myeloperoxidase antineutrophil cytoplasmic antibody-positive polyangiitis who developed sensorineural hearing loss and scleritis.

A 70-year-old woman was admitted to our hospital because of sudden hearing loss. She was treated with intratympanic dexamethasone, but her hearing impairment progressed. After admission, she developed scleritis of her left eye. Laboratory findings included elevated white blood cell count and C-reactive protein level, microhematuria, and proteinuria. Serology was positive for myeloperoxidase ant...

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The antineutrophil cytoplasmic antibody-associated vasculitides.

Wegener's granulomatosis, microscopic polyangiitis, and Churg-Strauss syndrome are small- to medium-vessel vasculitides linked by overlapping pathology and the presence of antineutrophil cytoplasmic antibodies (ANCA). Commonly referred to as the ANCA-associated vasculitides, these diseases are challenging to diagnose and to treat. Distinguishing the ANCA-associated vasculitides from other forms...

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Treatment of antineutrophil cytoplasmic antibody-associated vasculitis.

PURPOSE OF REVIEW The primary idiopathic small-vessel vasculitis syndromes include granulomatosis with polyangiitis, Churg-Strauss syndrome, and microscopic polyangiitis. These disorders are commonly referred to as antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides and prominently affect the pulmonary vasculature. Although significant progress has been made in the management of ...

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ژورنال

عنوان ژورنال: Australian and New Zealand Journal of Ophthalmology

سال: 1991

ISSN: 0814-9763,1440-1606

DOI: 10.1111/j.1442-9071.1991.tb01804.x